Last night, I ran a short (two hour) one-shot for Jamie and some friends who were almost completely new to role-playing. I decided to run GURPS, and I came up with a scenario loosely based on Russian folklore. It seemed to go over pretty well.
One thing I liked was the character sheet format I came up with for the pregenerated characters. I wanted to cut GURPS down to the bare essentials, so even though I built the characters using the full rules set, anything that didn't inform how to roleplay the character or present additional options was left off the sheet.
You can see the three sample characters I worked up here.